Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
7 July 1993 - 28 September 1994
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1995
Report Date:
1995

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes
Type of method:
flask method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Test material: Simazine (pure)
- Appearance: White powder
- Batch No.of test material: Ref 766
- Expiration date of the batch: Two years from date of manufacture
- Purity: 99.5%

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: In the dark at 4°C

Results and discussion

Water solubility
Key result
Water solubility:
0.005 g/L
Conc. based on:
test mat.
Incubation duration:
1 d
Temp.:
20 °C
Remarks on result:
other: Mean result
Remarks:
Standard deviation 4.63E-04 g/L
Details on results:
Calibration data gave a slope of 551977, an intercept of 53896 and a correlation coefficient of 0.99908, showing the detector response to be linear in the concentration range employed. Quality control data yielded a mean recovery of 102.0%.

Small peaks were observed at the retention volume of the test substance for the blank solutions, indicating the possibility of carryover.

Applicant's summary and conclusion

Conclusions:
The water solubility of simazine (pure) is 5.29E-03 g/L at 20°C.