Registration Dossier

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Data is from authoritatbve and modeling databases
Reference:
Composition 0
Composition 0
Composition 0
Composition 0
Composition 0
Composition 0
Qualifier:
according to
Guideline:
other: as mentioned below
Principles of method if other than guideline:
Estimation of octanol water partition coefficient of the test substance Anisoyl chloride.
GLP compliance:
not specified
Type of method:
other: No data available
Partition coefficient type:
octanol-water
Test material information:
Composition 1
Specific details on test material used for the study:
- Name of test material (IUPAC name): Anisoyl chloride
- Common name: 4-Methoxybenzoyl Chloride
- Molecular formula: C8H7ClO2
- Molecular weight: 170.5943 g/mol
- Smiles notation: c1(ccc(cc1)OC)C(=O)Cl
- InChl: 1S/C8H7ClO2/c1-11-7-4-2-6(3-5-7)8(9)10/h2-5H,1H3
- Substance type: Organic
- Physical state: Liquid
Key result
Type:
log Pow
Partition coefficient:
1.52
Remarks on result:
other: Other details not known
Details on results:
The logKow of test chemical Anisoyl chloride was estimated to be 1.52.
Conclusions:
The partition coefficient (log Pow) value of the substance Anisoyl chloride was estimated to be 1.52.
Executive summary:

The partition coefficient (log Pow) value of the substance Anisoyl chloride was estimated to be 1.52. Based on this value, chemical Anisoyl chloride can be considered to be hydrophilic in nature.

Description of key information

Based on the available data from authoritative and modelling databases, the partition coefficient (log Pow) value of the substance Anisoyl chloride was estimated to be 1.52. On the basis of this value, chemical Anisoyl chloride can be considered to be hydrophilic in nature.

Key value for chemical safety assessment

Log Kow (Log Pow):
1.52

Additional information

Based on the available data in a key study from authoritative and modelling databases, the partition coefficient (log Pow) value of the substance Anisoyl chloride was estimated to be 1.52.

Supporting study from modelling database indicates that the octanol water partition coefficient (log Pow) value of the substance Anisoyl chloride was estimated to be 1.821 ± 0.425 at 25°C.

Thus, based on the available information, the logPow valueof the test substance Anisoyl chloride ranges from 1.52 to 1.821, respectively. On the basis of this estimated value, chemical Anisoyl chloride can be considered to be hydrophilic in nature.