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Physical & Chemical properties

Density

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Reference
Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
October 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
The study was conducted according to an internationally recognised method. Test substance is adequately characterised. Therefore full validation applies.
Qualifier:
according to
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.3 (Relative Density)
Deviations:
no
GLP compliance:
no
Type of method:
oscillating densitimeter
Key result
Type:
density
Density:
0.897 g/cm³
Temp.:
20 °C
Remarks on result:
other:
Remarks:
density = 0.8972 ± 0,0002 g/ml at 20°C (relative density: D20/20 = 0,8989 ± 0,0002) . Mean value of two determinations
Key result
Type:
relative density
Density:
0.899 other: Unitless
Temp.:
20 °C
Remarks on result:
other:
Remarks:
D20/20

RESULTS

Determination 1

Density (d(20)): 0,8973 ± 0,0002 (g/ml)

Rel. density : D2020 0,8989 ± 0,0002

Determination 2:

Density (d(20)): 0,8972 ± 0,0002 (g/ml)

Rel. density : D20200,8989 ± 0,0002

Conclusions:
The test substance is less dense than water.
The mean relative density of the test item was D20/20 = 0,8989 ± 0,0002.
Executive summary:

The density of the test substance was measured according to OECD 109 / EU A3 guideline, using oscillating density meter. After calibration, two determinations were performed and the mean value was retained.

The relative density of the test item was measured as D20/20= 0,8989 ± 0,0002.

The result is consistent with the range reported in the European Pharmacopoeia 8.0 (0.890 -0.908)

Description of key information

The density of the test substance at 20°C was measured as 0.8973 g/cm3, and its relative density D(20/20) was measured as 0.8989 ± 0,0002.

The substance is less dense than water.

Key value for chemical safety assessment

Relative density at 20C:
0.899

Additional information

A fully reliable experimental study, conducted according to OECD 109 /EU A3 guideline, using oscillating density meter, is available. It is considered as a key study, and the result is retained as key data.

The relative density D(20/20) was measured as 0.8989 ± 0,0002.

The result is consistent with the range reported in the European Pharmacopoeia 8.0 (0.890 -0.908)