Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 231-836-6 | CAS number: 7758-19-2
Long-Evans rats were given access to 0, 1, 10 and 100 mg/L sodium chlorite in deionised water ad libitum as drinking water. Males were exposed 56 days, and females 14 days prior to breeding and throughout the 10-day breeding period. Adult males were necropsied after breeding. Dams and pups were necropsied at weaning and examined for thyroid hormone levels T3 and T4. The results of this study suggest that the young rat is more sensitive to the antithyroid effects of chlorite than is the adult. Decreases in serum T3 and T4 were observed on postnatal days 21 and 40 in male and female pups exposed to 100 pm sodium chlorite.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Close Do not show this message again