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EC number: 232-667-0 | CAS number: 9003-98-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
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- Auto flammability
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- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
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- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
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- Nanomaterial aspect ratio / shape
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- Endpoint summary
- Stability
- Biodegradation
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- Transport and distribution
- Environmental data
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- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
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- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
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- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
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- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Deoxyribonuclease was tested for acute toxicity, including read-across studies.
Fish: Deoxyribonuclease as not tested, however, Alpha-amylase was not toxic at the the tested concentration of 100 mg/L (58.3 mg aep/L) and thus the NOEC was determined to be 100 mg/L (58.3 mg aep/L). The LC50 value could not be determnined due to the absence of toxicity of the test compound at the tested concentration. Due to the similar nature of enzymes, similar results can be expected for the test substance deoxyribonuclease.
Daphnia magna: Exposure of freshwater invertebrate Daphnia magna to the test item has been investigated and gave the following results based on the geometric mean measured test concentrations:
EC50 = 1546 (932 – 2571) mg enzyme concentrate dry matter/L, equivalent to 214 mg active enzyme protein (aep)/L (analytically measured as aep).
NOEC = 852 mg enzyme concentrate dry matter/L.
LOEC = 1704 mg enzyme concentrate dry matter/L.
Algae: Exposure of Raphidocelis subcapitata to the test item gave the following results based on the geometric mean measured test concentrations:
EC50 = 59 (26 – 108) mg enzyme concentrate dry matter/L, equivalent to 8.1 mg active enzyme protein (aep)/L (analytically measured as aep).
NOEC = <5.3 mg enzyme concentrate dry matter/L.
LOEC = ≤5.3 mg enzyme concentrate dry matter/L.
Additional information
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