Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
flammable solids
Type of information:
experimental study
Adequacy of study:
key study
Study period:
March 02, 2005 to May 25, 2005
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
This study was conducted in compliance with the Swiss Ordinance relating to Good Laboratory Practice, adopted February 2nd, 2000 [RS 813.016.51. This Ordinance is based on the OECD Principles of Good Laboratory Practice, as revised in 1997 and adopted November 26th, 1997 by decision of the OECD Council [C(97)186/Final].

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2005
Report date:
2008

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.10 (Flammability (Solids))
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
Methyl 2,3-O-(1-methylethylidene)-5-O-[(4-methylphenyl)sulfonyl]-ß-D-ribofuranoside
EC Number:
609-920-2
Cas Number:
4137-56-8
Molecular formula:
C16H22O7S
IUPAC Name:
Methyl 2,3-O-(1-methylethylidene)-5-O-[(4-methylphenyl)sulfonyl]-ß-D-ribofuranoside
Details on test material:
Identity: Tosylfuranosid
Appearance: Solid / white
Storage: At room temperature at about 20°C
Expiration Date: July 31, 2005

Results and discussion

Flammable solids
Test procedure:
burning time (test type not further specified)
Remarks:
or specified in description of method (migrated information)
Remarks on result:
other: In contact with the ignition source, the test item Tosylfuranosid melted immediately and a brown coloured melt resulted. The test item could not be ignited.
Pyrophoric solids
Test procedure:
ignition time on contact with air
Remarks:
Ignition on contact with air refers to either Pyrophoric solids or Pyrophoric liquids depending on physical state (migrated information).
Remarks on result:
no ignition on contact with air (not further specified)
Remarks:
corresponding to 'no' in migrated source record.
Pyrophoric liquids
Test procedure:
ignition time on contact with air
Remarks:
Ignition on contact with air refers to either Pyrophoric solids or Pyrophoric liquids depending on physical state (migrated information).
Remarks on result:
no ignition on contact with air (not further specified)
Remarks:
corresponding to 'no' in migrated source record.

Any other information on results incl. tables

The determination of the flammability of the test item was performed in accordance with the EEC Directive 92/69, Part A, Methods for the determination of physico-chemical properties, A. 10 “Flammability (solids)”, EEC Publication No. L383, December 1992.

In contact with the ignition source, the test item Tosylfuranosid melted immediately and a brown coloured melt resulted. The test item could not be ignited.

In conclusion, the test item Tosylfuranosid is not “highly flammable” according to the criteria given in the guideline.

Applicant's summary and conclusion

Interpretation of results:
other: not “highly flammable” according to the criteria given in the guideline.
Conclusions:
The test item Tosylfuranosid is not “highly flammable” according to the criteria given in the guideline.
Executive summary:

The determination of the flammability of the test item was performed in accordance with the EEC Directive 92/69, Part A, Methods for the determination of physico-chemical properties, A. 10 “Flammability (solids)”, EEC Publication No. L383, December 1992.

In contact with the ignition source, the test item Tosylfuranosid melted immediately and a brown coloured melt resulted. The test item could not be ignited.

In conclusion, the test item Tosylfuranosid is not “highly flammable” according to the criteria given in the guideline.