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EC number: 237-600-9
CAS number: 13863-31-5
* The scores for 48 hrs were not measured
during the test and not reported in the report. The scores for the 48
hrs were inserted in the below table duplicating the highest score for
each animal and the mean scores were calculated based on these values
for the calculation purposes as required by CLP
Skin Irritation - Intact skin
Mean (24,48,72 hrs)
Skin reactions - abraded skin
The skin irritation potential was
assessed following the procedure of the patch-test technique described
in the "Appraisal of the Safety of Chemicals in Foods, Drugs and
Cosmetics" (1959) of the US Association of Food and Drug Officials
Primary irritation index was estimated to
be 1.2; mild irritating.
Discussion and conclusion
The scoring system criteria used to record
the hardness of the skin reactions followed in the current test are the
same as those reported into the OECD guideline, therefore it is possible
to re-evaluate the results, because the raw tables are included into the
Despite the reaction scores at 48 hours
were not reported, the mean value scored is reasonably expected to be
less than 2.3 for erythema/eschar and for oedema in at least 2 of 3
tested animals, in both intact and abraded skin, from gradings at 24, 48
and 72 hours after patch removal.
In conclusion, it is reasonable to NOT
classify the substance as skin irritant according to the CLP Regulation
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