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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

Because the test substance was not stable in the test medium, the validation was related to double hydrolysed product (main hydrolytic product, which is more stable in the dilution

water) according to Guidance Document on Aquatic Toxicity Testing of Difficult Substances and Mixtures (OECD SERIES ON TESTING AND ASSESSMENT No. 23). The analytical

determination of the test substance concentrations will also be based on this double hydrolysed product.

Because concentrations of the double hydrolysed product (in the two highest concentrations) have not been satisfactorily maintained within ± 20 percent of the nominal or measured initial

concentration throughout the test, geometric means of measured concentrations were used for evaluations and results.

The evaluation using geometric means of measured concentrations:

72 hour - ErC50 = not evaluated (95% confidence limit: not evaluated)

72 hour - EyC50 = 2.81 mg· L-1 (95% confidence limit: 0.187 - 47.8 mg· L-1)

72 hour - ErC10 = 0.308 mg· L-1 (95% confidence limit: 0.078 - 1.22 mg· L-1)

72 hour - EyC10 = 0.007 mg· L-1 (95% confidence limit: 0.00 I -0.096 mg· L-1)

72 hour - NOECr < 3.26 mg· L-1

72 hour - NOECy < 3.26 mg· L-1

The evaluation using initial measured concentrations:

72 hour - ErC50 = 67.9 mg· L-1 (95% confidence limit: 12.2 - 338 mg· L- 1)

72 hour - EyC50 = 3.84 mg· L-1 (95% confidence limit: 0. 718 - 21.7 mg· L-1)

72 hour - ErC10 = 2.44 mg· L-1 (95% confidence limit: 0.674 - 8.86 mg· L-1)

72 hour - EyC10 = 0.062 mg· L-1 (95% confidence limit: 0.013 - 0.288 mg· L-1)

72 hour - NOECr < 2.9 mg· L-1

72 hour - NOECy < 2.9 mg· L-1

Key value for chemical safety assessment

EC50 for freshwater algae:
67.9 mg/L
EC10 or NOEC for freshwater algae:
2.44 mg/L

Additional information