Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report Date:
2012

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
not specified
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Study design

Analytical method:
photometric method

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
2.9
Temp.:
23 °C
pH:
ca. 7.3

Any other information on results incl. tables

Table 1: Results in detail

determ. no

     stock solution [ml]   n-octanol [ml]     test substance conc. in n-octanol phase [mg/l]    test substance conc. in water phase [mg/l]   log Pow   
  A1     5  10 722,1  0,54  3,1 
 A2    5  10 719,7  0,56  3,1 
B1  10   10  719,1  0,95  2,9 
 B2   10    10 716,7  0,94  2,9 
 C1   20   10  721,5  1,57  2,7
 C2   20   10  728,7  1,57  2,7 

mean

 ---  ---  ---  --- 2,9 

Stock solution: 1225 mg/l

Conc. of filtered stock solution: 750 mg/l

Applicant's summary and conclusion

Conclusions:
The logPow of this substance was determined as 2.9.