Registration Dossier

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Additional information

Based on available data, Anthraquinone was absorbed from the gastrointestinal tract and distributed to tissues. No indication of Anthraquinone bioaccumulation was apparent in any tissue. The majority of the radiolabel was eliminated in the feces and the urine. At 96 hours after dosing, less than 5% of the administered dose remained in major tissues. Elimination of over 50% of the administered radioactivity was found in the feces. There seemed to be an extensive hepatic metabolism of Anthraquinone. Analysis of urine revealed the presence of 11 metabolites, with 1-hydroxyAnthraquinone and 2-hydroxy Anthraquinone being the major ones.