Registration Dossier
Registration Dossier
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EC number: 201-549-0 | CAS number: 84-65-1
Endpoint summary
Administrative data
Description of key information
Additional information
Experimental short term toxicity studies are waived because of highly insolubility of anthraquinone in water (In accordance with REACH Regulation (EC) No 1907/2006, Annex VII and Annex VIII, the studies do not need to be conducted if the substance is highly insoluble in water. Seeing that the solubility is 74.6 micrograms per liter, substance meets the criteria for insolubility.) The long-term aquatic toxicity studies are considered (testing proposal).
There are five acute toxicity studies available (three for fish, one acute toxicity study to freshwater invertebrates and one for marine organisms) with reliable results and where selection of the test concentrations was based on the limit of water solubility of Anthraquinone. Based on these data, it was established that under the conditions maintained during the studies Anthraquinone is not acutely toxic to fish, daphnids and eastern oysters at and below the material's limit of water solubility.
No reliable standard microbial inhibition test data are available. Results of toxicity study of anthraquinone to microorganisms are above water solubility, thus the test result has to be considered as unreliable.
Estimation of PNECs value is therefore impossible, and also the estimated L(E)C50 can only be used as an indication of the short-term toxicity of the chemical considered.
The chemical safety assessment according to Annex I of REACH indicates the need to investigate further the effects on aquatic organisms, due to low water solubility of a substance, long-term tests should be performed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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