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EC number: 200-609-3 | CAS number: 65-45-2
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 6 July 2010
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The substance is soluble in the dispersion medium. Conducting the experiment in a saturated solution limited dissolution of the bulk material, however, the reported particle size distribution is expected to be associated with increased uncertainty.
- Qualifier:
- according to guideline
- Guideline:
- other: CIPAC Method 187, Particle size analysis by laser diffration
- GLP compliance:
- no
- Type of method:
- Laser scattering/diffraction
- Type of distribution:
- counted distribution
- Percentile:
- D50
- Mean:
- 796 µm
- Remarks on result:
- other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.
- Percentile:
- D10
- Mean:
- 209 µm
- St. dev.:
- 26
- Percentile:
- D50
- Mean:
- 796 µm
- St. dev.:
- 18
- Percentile:
- D90
- Mean:
- 1 480 µm
- St. dev.:
- 11
- Conclusions:
- While conducting the experiment in a saturated solution may have limited dissolution of the bulk material, the reported distribution of small particles present in the sample is expected to have increased uncertainty. Both crystallite growth and dissolution are potential outcomes. However, considering the large size of the particles (D50 ca. 1mm, and in good agreement with visual observation) the results are considered to be adequate for the purposes of risk assessment.
Reference
Average of three determinations. Standard deviation is of the three determinations.
Description of key information
D50 ca. 1mm, CIPAC Method 187, laser diffraction, Das 2010
Additional information
While conducting the experiment in a saturated solution may have limited dissolution of the bulk material, the reported distribution of small particles present in the sample is expected to be unreliable. Both crystallite growth and dissolution are potential outcomes. However, considering the large size of the particles (D50 ca. 1 mm, and in good agreement with visual observation) the results are considered to be adequate for the purposes of risk assessment.
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