Registration Dossier
Registration Dossier
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EC number: 611-390-2 | CAS number: 56467-43-7
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 29.01.2010 to 12.03.2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- adopted July, 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- May 2008
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- column elution method
- Specific details on test material used for the study:
- 4-(Methacryloyloxy)bezophenone: 97.26%
Benzophenone acetate: 1.95 % - Key result
- Water solubility:
- 4 mg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- >= 6.2 - <= 6.4
- Details on results:
- Method:
The water solubility of the test item was estimated using the column elution method. The saturation mass concentration of the test item
was determined using a HPLC method.
Result of the Preliminary Test (nonGLP):
The water solubility of the test item was estimated to be below 10 mg/L.
Result of the Main Test:
The saturation concentration of the test item was estimated using HPLC method. The linearity of the analytical method was proved in the concentration range from 0.5 to 15 mg test item!L. The regression coefficient (r2) was determined to be 0.9998.
Corresponding to the analysis the water solubility of the test item at 20 ± 1 °C was determined to be 4 mg/L. - Conclusions:
- Corresponding to the analysis the water solubility of4-(Methacryloyloxy)benzophenone at 20 ± 1 °C was determined to be 4 mg/L.
- Executive summary:
The water solubilty of 4 -(Methacryloyloxy)benzophenone is reported to be 4 mg/l at 20 +/- 1°C according to OECD guideline 105, adopted July 1995 and EU Method A., May 2008; column elution method.
Reference
Description of key information
Key value for chemical safety assessment
- Water solubility:
- 4 mg/L
- at the temperature of:
- 20 °C
Additional information
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