Registration Dossier

Toxicological information

Specific investigations: other studies

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Administrative data

Endpoint:
specific investigations: other studies
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies

Data source

Reference
Reference Type:
publication
Title:
Biological activity of phenolic compounds. Hepatic cytochrome P-450, cytochrome b5, and NADPH cytochrome c reductase in Chicks and rats fed phenolic monomers, polymers, and glycosides (42134)
Author:
Klasing SA, Mora MI, Wilson WC, Fahey GC, Garst JE
Year:
1985
Bibliographic source:
Proceedings of the Society for Experimental Biology and Medicine, 179, 529-538

Materials and methods

Test guideline
Qualifier:
no guideline required
GLP compliance:
not specified
Type of method:
in vivo

Test material

Constituent 1
Reference substance name:
Automatically generated during migration to IUCLID 6, no data available
IUPAC Name:
Automatically generated during migration to IUCLID 6, no data available
Details on test material:
- Test material identity: vanillin from Sigma Corp., St Louis, MO (no other information available)

Results and discussion

Any other information on results incl. tables

RS-Freetext:
Inclusion of 0.5% vanillin in diet of chicks had no effect on animal  performance or hepatic measurements compared with controls.

Applicant's summary and conclusion