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Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017-03-20 to 2017-05-15
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: isothermal thermogravimetry

Test material

Constituent 1
Chemical structure
Reference substance name:
(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid hydrate
EC Number:
680-378-7
Cas Number:
138624-11-0
Molecular formula:
C4H15NO8P2
IUPAC Name:
(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid hydrate
Test material form:
solid: particulate/powder
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and batch number: Sponsor and GTH-610
- Purity test date: 2016-04-16

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: At room temperature protected from light

TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing: 10.4 and 15.0 mg samples of test material were each placed into a suspension of n-hexane and applied to the surface of a roughened glass plate as a homogenous layer.

FORM AS APPLIED IN THE TEST (if different from that of starting material)
10.4 and 15.0 mg samples of test material were each placed into a suspension of n-hexane and applied to the surface of a roughened glass plate as a homogenous layer.

Results and discussion

Vapour pressureopen allclose all
Key result
Test no.:
#1
Temp.:
ca. 20 °C
Vapour pressure:
< 0 Pa
Key result
Test no.:
#2
Temp.:
ca. 25 °C
Vapour pressure:
< 0 Pa
Transition / decomposition
Key result
Transition / decomposition:
yes
Transition temp.:
> 190 °C
Vapour pressure at 10°C below transition temperature:
0.23 Pa
Vapour pressure at 20°C below transition temperature:
0.18 Pa

Applicant's summary and conclusion

Conclusions:
The vapor pressure of the test substance was determined according to guideline criteria to be < 8.4*10^-7 Pa at 20 degrees Celsiues and < 1.1 * 10^-6 at 25 degrees Celsius.