(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid;hydrate

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2017-03-20 to 2017-05-15

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2017

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

no

Test guideline 3

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7950 (Vapor Pressure)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

effusion method: isothermal thermogravimetry

Test material

Test material information

Constituent 1

Reference substance name:

(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid hydrate

EC Number:

680-378-7

Cas Number:

138624-11-0

Molecular formula:

C4H15NO8P2

IUPAC Name:

(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid hydrate

Test material form:

solid: particulate/powder

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and batch number: Sponsor and GTH-610
- Purity test date: 2016-04-16

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: At room temperature protected from light

TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing: 10.4 and 15.0 mg samples of test material were each placed into a suspension of n-hexane and applied to the surface of a roughened glass plate as a homogenous layer.

FORM AS APPLIED IN THE TEST (if different from that of starting material)
10.4 and 15.0 mg samples of test material were each placed into a suspension of n-hexane and applied to the surface of a roughened glass plate as a homogenous layer.

Results and discussion

Vapour pressure

Vapour pressure 1

Key result

Test no.:

#1

Temp.:

ca. 20 °C

Vapour pressure:

< 0 Pa

Vapour pressure 2

Key result

Test no.:

#2

Temp.:

ca. 25 °C

Vapour pressure:

< 0 Pa

Transition / decomposition

Key result

Transition / decomposition:

yes

Transition temp.:

> 190 °C

Vapour pressure at 10°C below transition temperature:

0.23 Pa

Vapour pressure at 20°C below transition temperature:

0.18 Pa

Applicant's summary and conclusion

Conclusions:

The vapor pressure of the test substance was determined according to guideline criteria to be < 8.4*10^-7 Pa at 20 degrees Celsiues and < 1.1 * 10^-6 at 25 degrees Celsius.