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Physical & Chemical properties

Dissociation constant

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Description of key information

pKa: 12.06-12.26 at 25 °C

Key value for chemical safety assessment

pKa at 20°C:

Additional information

The pKa values for three representative structures were estimated with the SPARC online calculator, recommended in Chapter 7.1.17 of the Guidance on Information Requirements and Chemical Safety Assessment. Since no ionised species are predicted in the pH range 5-9, the estimated pKa values are acceptable for use in the Chemical Safety Assessment according to the integrated testing strategy developed in the Guidance mentioned above.