Registration Dossier

Administrative data

Endpoint:
dermal absorption, other
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Scientifically acceptable calculation.

Data source

Reference
Reference Type:
other: QSAR calculation
Title:
Unnamed
Year:
2014
Report date:
2014

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
QSAR calculation using SkinPerm v1.03
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2'-dimethyl-4,4'-methylenebis(cyclohexylamine)
EC Number:
229-962-1
EC Name:
2,2'-dimethyl-4,4'-methylenebis(cyclohexylamine)
Cas Number:
6864-37-5
Molecular formula:
C15H30N2
IUPAC Name:
2,2'-dimethyl-4,4'-methylenebis(cyclohexylamine)

Results and discussion

Percutaneous absorption
Remarks on result:
other: maximal absorption: 0.00257 mg/cm2/h

Applicant's summary and conclusion