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Registration Dossier
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EC number: 204-680-1 | CAS number: 124-10-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- other: review article
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Review article
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission Flavouring Group Evaluation 2, Revision 1 (FGE.02Rev 1)
- Author:
- European Food Safety Authority
- Year:
- 2 008
- Bibliographic source:
- http://www.efsa.europa.eu/; The EFSA Journal (2008) 709-60
- Report date:
- 2007
- Reference Type:
- review article or handbook
- Title:
- Flavouring substances and natural sources of flavourings.
- Author:
- CoE (Council of Europe)
- Year:
- 1 992
- Bibliographic source:
- 4th Ed. vol. I. Chemically defined flavouring substances. Council of Europe, partial agreement in the social and public health field. Strasbourg.
- Reference Type:
- review article or handbook
- Title:
- Evaluation of certain food additives and contaminants.
- Author:
- JECFA
- Year:
- 1 999
- Bibliographic source:
- Forty-ninth report of the Joint FAO/WHO Expert Committee on Food Additives. Rome, 17-26 June 1997. WHO Technical Report Series, no. 884. Geneva.
- Reference Type:
- review article or handbook
- Title:
- First annual report on chemically defined flavouring substances.
- Author:
- SCF (Scientific Committee for Food)
- Year:
- 1 995
- Bibliographic source:
- May 1995, 2nd draft prepared by the SCF Working Group on Flavouring Substances (Submitted by the SCF Secretariat, 17 May 1995). CS/FLAV/FL/140-Rev.2. Annex 6 to Document III/5611/95, European Commission, Directorate-General III, Industry.
Materials and methods
- Type of study / information:
- The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (the Panel) is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Scientific Panel is asked to evaluate 47 flavouring substances in the Flavouring Group Evaluation 2, Revision 1 (FGE.02Rev1), using the procedure as referred to in the Commission Regulation (EC) No 1565/2000. These 47 flavouring substances belong to chemical groups 1 and 2, Annex I of the Commission Regulation (EC) No 1565/2000.
Test material
- Reference substance name:
- Methyl myristate
- EC Number:
- 204-680-1
- EC Name:
- Methyl myristate
- Cas Number:
- 124-10-7
- Molecular formula:
- C15H30O2
- IUPAC Name:
- methyl myristate
- Details on test material:
- - Name of test material (as cited in study report): Methyl tetradecanoate
- CAS-No. of test material (as cited in study report): 124-10-7
- FL-No. of test material (as cited in study report):09.106
Constituent 1
Results and discussion
Any other information on results incl. tables
According to the default MSDI ( Maximised Survey-derived Daily Intake) approach, the 47 flavouring substances in this group have intakes in Europe from 0.0012 to 6.7 µg/capita/day, which are below the threshold of concern value for a structural class I substance of 1800 µg/person/day.
MSDI for Methyl tetradecanoate: 54 µg/capita/day.
SCF status: Category 1 (Considered safe in use)
JECFA status: No safety concern (No safety concern at estimated levels of intake)
CoE status: Category B (Flavouring substance which can be used provisionally in foodstuffs)
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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