Registration Dossier

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1991-07-23 - 1991-08-22
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: GLP Guideline study, some deficiencies (no analytical monitoring)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1991
Report Date:
1991

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
liquid
Lot No. 3/90 (24.04.1990)
insoluble in water

Sampling and analysis

Analytical monitoring:
no

Test solutions

Vehicle:
no
Details on test solutions:
Test concentrations: 10-18-32-58-100-180 mg/L

Test organisms

Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)
Details on test organisms:
Supplier: Zoo-Stumpe, D-3200 Hildesheim
Length 3.0-3.2 cm
Weight: 0.33 g/fish
Feed: TeraMin, Fa. Tetra

Study design

Test type:
semi-static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h
Post exposure observation period:
no

Test conditions

Test temperature:
23 +/- 2 deg C
pH:
7.86 (0h) - 8.16 (96h)
Dissolved oxygen:
Degree of oxygen saturation: 96-99%

Results and discussion

Effect concentrations
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
In a dose response OECD 203 acute fish toxicity test with the registration substance a LC50 (96h) of 100 mg/L was derived.