Registration Dossier
Registration Dossier
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EC number: 701-162-1 | CAS number: -
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1991-07-23 - 1991-08-22
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: GLP Guideline study, some deficiencies (no analytical monitoring)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 991
- Report date:
- 1991
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- 6-[3-(C12-C18)-alkenyl(branched, unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid
- EC Number:
- 701-162-1
- Molecular formula:
- C22H37NO4 - C28H49NO4
- IUPAC Name:
- 6-[3-(C12-C18)-alkenyl(branched, unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid
- Details on test material:
- liquid
Lot No. 3/90 (24.04.1990)
insoluble in water
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
- Details on test solutions:
- Test concentrations: 10-18-32-58-100-180 mg/L
Test organisms
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- Supplier: Zoo-Stumpe, D-3200 Hildesheim
Length 3.0-3.2 cm
Weight: 0.33 g/fish
Feed: TeraMin, Fa. Tetra
Study design
- Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Post exposure observation period:
- no
Test conditions
- Test temperature:
- 23 +/- 2 deg C
- pH:
- 7.86 (0h) - 8.16 (96h)
- Dissolved oxygen:
- Degree of oxygen saturation: 96-99%
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- In a dose response OECD 203 acute fish toxicity test with the registration substance a LC50 (96h) of 100 mg/L was derived.
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