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Boiling point

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Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 15 to 19 Septembre 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
The study was conducted according to an internationally recognised method, and under GLP. The test substance is adequately characterised. Therefore full validation applies.
Qualifier:
according to
Guideline:
OECD Guideline 103 (Boiling Point)
Version / remarks:
1995
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.2 (Boiling Temperature)
Version / remarks:
2008
Deviations:
no
Principles of method if other than guideline:
Not applicable
GLP compliance:
yes (incl. certificate)
Remarks:
GLP compliance programme (inspected on 13-14 October 2014 / signed on 8 April 2015)
Type of method:
method according to Siwoloboff
Key result
Boiling pt.:
ca. 190.4 °C
Atm. press.:
ca. 101 325 Pa
Decomposition:
no
Remarks:
After cooling down a slightly change of the colour was observed.
Remarks on result:
other:
Remarks:
Mean ± standard deviation (after correction following Sydney Young) = 190.4 ± 0.3 °C (463.5 ± 0.3 K) at standard pressure (101.325 kPa).

The measured values and observations are presented in the following tables.

Table 4.3.1    Results

Determination

Boiling Point

Atmospheric Pressure

First determination

190.0 °C (463.2 K)

99787 Pa

Second determination

189.6 °C (462.8 K)

99759 Pa

 

Table 4.3.2    Observations

Observations

Temp. in °C

First Determination

Temp. in °C

Second Determination

When setting the sample tube into an aluminium block came now and then bubbles, after that the bubbles disappeared.

176.2

176.2

Bubble chain, heating plate turned off

203.2

201.4

 

After cooling down a slightly change of the colour was observed.

 Table 4.3.3    Corrected values following Sidney-Young

 

Boiling point

Pressure in Pa

Corrected Boling point

First determination

190.0 °C (463.0 K)

99787 Pa

190.59 °C (463.74 K)

Second determination

189.6 °C (462.8 K)

99757 Pa[SRD1] 

190.20°C (463.35 K)

Mean

 

 

190.4 °C (463.5 K)

 

As the difference between the two determinations was below 2 K the result can be considered valid and theresult is calculated as mean of the two values of the duplicate determination.

Mean ± standard deviation (after correction following Sydney Young) = 190.4 ± 0.3 °C (463.5 ± 0.3 K) at standard pressure (101.325 kPa).

Conclusions:
The initial boiling temperature of the test item has been determined to be ca 190.4± 0.3 °C, corrected to standard pressure (101.325 kPa).
Executive summary:

The initial boiling point of the test item was measured under GLP according to OECD 103 / EU A2 guideline, by Siwoloboff.

The test item was filled into a sample tube. The sample tube was then set into the aluminium block at 176.2 °C (first and second determination). For the increase of the temperature, a temperature gradient of 1 °C /min was maintained. When bubbles rose constantly on the capillary, heating was turned down, and, cooling slowly. The temperature at which the chain of bubbles broke was recorded (with its atmospheric pressure) and is considered as the boiling point.The determination was performed in duplicate.

After cooling down a slightly change of the colour was observed.

Description of key information

The initial boiling point of the test item has been determined to be ca 190.4 ± 0.3 °C, corrected to standard pressure (101.325 kPa).

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
190.4 °C

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. It is considered as a key study.