Registration Dossier
Registration Dossier
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EC number: 216-245-3 | CAS number: 1533-45-5
Endpoint summary
Administrative data
Description of key information
Bioaccumulation: aquatic / sediment
BCFBAF model of Estimation Programs Interface was used to predict the bioconcentration factor (BCF) of test chemical. The bioconcentration factor (BCF) of test chemical was estimated to be 7541 L/kg whole body w.w (at 25 deg C) which exceeds the bio concentration threshold of 5000, indicating that the test chemical is expected to be very bioaccumulate in the food chain.
Additional information
Bioaccumulation: aquatic / sediment
Various predicted data of the test chemical were reviewed for the bioaccumulation end point which are summarized as below:
In a prediction done using the BCFBAF Program of Estimation Programs Interface was used to predict the bioconcentration factor (BCF) of test chemical. The bioconcentration factor (BCF) of test chemical was estimated to be 7541 L/kg whole body w.w (at 25 deg C) which exceeds the bio concentration threshold of 5000, indicating that the test chemical is expected to be very bioaccumulate in the food chain.
In an another prediction done by using Bio-concentration Factor module (ACD (Advanced Chemistry Development)/I-Lab predictive module, 2017)), the Bio-concentration Factor of the test chemical was estimated to be 10337, 308937, 1171078, 1439508, 1471549, 1474815, 1475142, 1475174 and 1475177 at pH range 0, 1, 2, 3, 4, 5, 6, 7 and 8-14, respectively. This value indicates that the test chemical was considered to be very bioaccumulative in aquatic organisms.
Another predicted data was estimated using SciFinder database (American Chemical Society (ACS), 2017) for predicting the bioconcentration factor (BCF) of test chemical. The bioconcentration factor (BCF) of test chemical was estimated to be 1330, 5880, 7450, 7640 and 7660 at pH range 1, 2, 3, 4 and 5-10 respectively (at 25 deg C) which exceeds the bio concentration threshold of 5000 (at pH 7.0), indicating that the test chemical is expected to be very bioaccumulate in the food chain.
On the basis of above results for test chemical (from modelling databases, 2017), it can be concluded that the BCF value of test substance ranges from7541 to 1475174 (at pH 7.0), which exceeds the bioconcentration threshold of 5000, indicating that the test chemical is expected to be very bioaccumulate in the food chain.
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