14H-benz[4,5]isoquino[2,1-a]perimidin-14-one

Density

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Deviations:

no

Qualifier:

equivalent or similar to guideline

Guideline:

EU Method A.3 (Relative Density)

Deviations:

not applicable

GLP compliance:

yes (incl. QA statement)

Type of method:

other: by displacement

Key result

Type:

relative density

Density:

1.402

Temp.:

20 °C

Remarks on result:

other: mean value of 2 determinations

Literature data (CRC Handbook of Chemistry and Physics 75th Edition):

d (20, w) (density of water at 20 °C) = 0.9982 g/mL

d (4, w) (density of water at 4 °C) = 0.99997 g/mL

d (20, a) (density of air at 20 °C) = 0.0012 g/mL

Conclusions:

The relative density of solvent red 179 compared to the density of water was determined to be 1.402 at 20 °C.

Executive summary:

The determination of the Physico-Chemical properties was based on the OECD Guidelines for Testing of Chemicals, Section 1 – Physical-Chemical Properties No: 109 “Density of Liquids and Solids“ and to Council Regulations EC No 440/2008, Guideline Part A – Methods for the Determination of Physico-Chemical Properties, A.3. “Relative density”. The relative density was determined by displacement method. The solid sample was weighed into a pycnometer (or vial) and by displacement of a solvent, its equivalent volume is determined to calculate the density. The relative density of solvent red 179 was determined by comparing the ratio of density of the test substance to the density of water. The relative density of the test item compared to the density of water was determined to be 1.402 (mean value of 2 determinations) measured at 20 °C.

Reference 2

Endpoint:

bulk density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2014

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Qualifier:

according to guideline

Guideline:

other: DIN ISO 697 ‘Determination of apparent density – method by measuring the mass of a given volume’ (J1984)

Deviations:

no

GLP compliance:

no

Other quality assurance:

ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)

Type of method:

other: volumetric method

Type:

bulk density

Density:

0.224 other: kg/L

Temp.:

20 °C

Results:

Temperature	Test Run	Density	Arithmetic Mean
[°C]		[kg/L]	[kg/L]
	1	0.230
20	2	0.220	0.224
	3	0.223

Conclusions:

The bulk density of 14H-benz[4,5]isoquino[2,1-a]perimidin-14-one is found to be ρbulk = 0.224 kg/L at 20 °C.

Executive summary:

The test to measure the bulk density of 14H-benz[4,5]isoquino[2,1-a]perimidin-14-one was performed as stipulated in DIN ISO 697 ‘Determination of apparent density – method by measuring the mass of a given volume’ (1984).

For free-flowing solids (in this case a powder) commonly the bulk density is determined instead of the relative densitiy.

The bulk density of 14H-benz[4,5]isoquino[2,1-a]perimidin-14-one is found to be ρbulk = 0.224 kg/L at 20 °C.

Description of key information

The relative density of solvent red 179 compared to the density of water was determined to be 1.402 (mean value) measured at 20 °C. The bulk density of solvent red 179 was found to be ρbulk = 0.224 kg/L at 20 °C.

Key value for chemical safety assessment

Relative density at 20C:

1.402

Additional information

The relative density of the test item was determined by comparing the ratio of density of the test substance to the density of water. For free-flowing solids (in this case a powder) commonly the bulk density is determined instead of the relative densitiy.