Registration Dossier

Physical & Chemical properties

Density

Currently viewing:

Administrative data

Link to relevant study record(s)

Referenceopen allclose all

Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Deviations:
no
Qualifier:
equivalent or similar to
Guideline:
EU Method A.3 (Relative Density)
Deviations:
not applicable
GLP compliance:
yes (incl. certificate)
Type of method:
other: by displacement
Key result
Type:
relative density
Density:
1.402
Temp.:
20 °C
Remarks on result:
other: mean value of 2 determinations

Literature data (CRC Handbook of Chemistry and Physics 75th Edition):

d (20, w) (density of water at 20 °C) = 0.9982 g/mL

d (4, w) (density of water at 4 °C) = 0.99997 g/mL

d (20, a) (density of air at 20 °C) = 0.0012 g/mL

Conclusions:
The relative density of solvent red 179 compared to the density of water was determined to be 1.402 at 20 °C.
Executive summary:

The determination of the Physico-Chemical properties was based on the OECD Guidelines for Testing of Chemicals, Section 1 – Physical-Chemical Properties No: 109 “Density of Liquids and Solids“ and to Council Regulations EC No 440/2008, Guideline Part A – Methods for the Determination of Physico-Chemical Properties, A.3. “Relative density”. The relative density was determined by displacement method. The solid sample was weighed into a pycnometer (or vial) and by displacement of a solvent, its equivalent volume is determined to calculate the density. The relative density of solvent red 179 was determined by comparing the ratio of density of the test substance to the density of water. The relative density of the test item compared to the density of water was determined to be 1.402 (mean value of 2 determinations) measured at 20 °C.

Endpoint:
bulk density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2014
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Qualifier:
according to
Guideline:
other: DIN ISO 697 ‘Determination of apparent density – method by measuring the mass of a given volume’ (J1984)
Deviations:
no
GLP compliance:
no
Other quality assurance:
ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
Type of method:
other: volumetric method
Type:
bulk density
Density:
0.224 other: kg/L
Temp.:
20 °C

Results:

Temperature   Test Run  Density  Arithmetic Mean
 [°C]    [kg/L]  [kg/L]
   1  0.230  
 20  2  0.220  0.224
   3  0.223  
Conclusions:
The bulk density of 14H-benz[4,5]isoquino[2,1-a]perimidin-14-one is found to be ρbulk = 0.224 kg/L at 20 °C.
Executive summary:

The test to measure the bulk density of 14H-benz[4,5]isoquino[2,1-a]perimidin-14-one was performed as stipulated in DIN ISO 697 ‘Determination of apparent density – method by measuring the mass of a given volume’ (1984).

For free-flowing solids (in this case a powder) commonly the bulk density is determined instead of the relative densitiy.

The bulk density of 14H-benz[4,5]isoquino[2,1-a]perimidin-14-one is found to be ρbulk = 0.224 kg/L at 20 °C.

Description of key information

The relative density of solvent red 179 compared to the density of water was determined to be 1.402 (mean value) measured at 20 °C. The bulk density of solvent red 179 was found to be ρbulk = 0.224 kg/L at 20 °C.

Key value for chemical safety assessment

Relative density at 20C:
1.402

Additional information

The relative density of the test item was determined by comparing the ratio of density of the test substance to the density of water. For free-flowing solids (in this case a powder) commonly the bulk density is determined instead of the relative densitiy.