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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Additional information

No data were traced concerning thioglycolic acid toxicity to microorganisms. In 2004, the assessment of the inhibitory effect of Ammonium thioglycolate on the respiration of activated sewage sludge

was carried out by Clarke according to OECD Guideline 209 and GLP requirements. Based on the results of this study, the effect of the test material on the respiration of activated sewage sludge micro-organisms gave a 3-Hour EC50 of 530 mg ai/l. The No Observed Effect Concentration (NOEC) after 3 hours exposure was 32 mg ai/l. EC50 -30min was of 820 mg/L. Thioglycolic acid would be expected to exist in its ionized form under most environmental conditions, and it is reasonable to expect that the acid and its salt will behave similarly in the environment. This result could therefore be suitable for addressing thioglycolic acid potential effects on microorganisms. Nevertheless as thioglycolic acid is ready biodegradable this test should not be required according to REACH.