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Toxicity to microorganisms

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Key value for chemical safety assessment

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No data were traced concerning thioglycolic acid toxicity to microorganisms. In 2004, the assessment of the inhibitory effect of Ammonium thioglycolate on the respiration of activated sewage sludge

was carried out by Clarke according to OECD Guideline 209 and GLP requirements. Based on the results of this study, the effect of the test material on the respiration of activated sewage sludge micro-organisms gave a 3-Hour EC50 of 530 mg ai/l. The No Observed Effect Concentration (NOEC) after 3 hours exposure was 32 mg ai/l. EC50 -30min was of 820 mg/L. Thioglycolic acid would be expected to exist in its ionized form under most environmental conditions, and it is reasonable to expect that the acid and its salt will behave similarly in the environment. This result could therefore be suitable for addressing thioglycolic acid potential effects on microorganisms. Nevertheless as thioglycolic acid is ready biodegradable this test should not be required according to REACH.