Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 248-698-8 | CAS number: 27859-58-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 24 November 2015 to 9 September 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: Knudsen cell
- Key result
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Conclusions:
- Under the conditions of the study, the vapour pressure of the test material was determined to be 1.162×10^-4 Pa at 20 °C and 1.933×10^-4 Pa at 25 °C.
- Executive summary:
The vapour pressure of the test material was investigated in a study which was performed under GLP conditions and in accordance with the standardised guideline OECD 104.
The experimental procedure followed the Knudsen cell effusion method. A small quantity of the test substance (nominally 7-9 mg) was placed in each of two weighed aluminium crucibles and a lid, with an orifice of a nominal 1 mm diameter (accurately measured), cold-welded on. The crucibles were weighed to an accuracy of 1 µg and placed in the apparatus, which was then evacuated to ultra-high vacuum. At set time intervals, the apparatus was brought to atmospheric pressure, the crucibles reweighed and the loss in mass of test substance from each calculated. The vapour pressure ¿ (Pa) was calculated using the Hertz-Knudsen relationship. Tests were conducted between 58 and 94 °C to ensure that test substance remained in the liquid phase throughout the test period. The vapour pressures at 20 °C and 25 °C were then extrapolated from the vapour pressure-temperature plots.
Under the conditions of the study, the vapour pressure of the test material was determined to be 1.162×10^-4 Pa at 20 °C and 1.933×10^-4 Pa at 25 °C.
Reference
The test was performed from 58 to 94 °C. The vapour pressure of the test material was 1.162×10^-4 Pa at 20 °C and 1.933×10^-4 Pa at 25 °C, extrapolated from the Ln VP vs 1/T graph.
The IR spectra for the tested, control and untested material revealed no differences, therefore the test material was considered stable for the duration of the test.
Table 1: Vapour Pressure (VP) Calculations
Temp (°C) |
Crucible weight |
Vapour Pressure |
1/T (K-1) |
Ln (VP) |
|||
Test 1 (mg) |
Test 2 (mg) |
Test 1 (Pa) |
Test 2 (Pa) |
Test 1 |
Test 2 |
||
58.0 |
55.381 |
56.701 |
9.403E-03 |
7.199E-03 |
3.020E-03 |
-4.667E+00* |
-4.934E+00* |
55.289 |
56.630 |
||||||
58.0 |
55.289 |
56.630 |
3.263E-03 |
4.971E-03 |
3.020E-03 |
-5.725E+00 |
-5.304E+00 |
55.261 |
56.587 |
||||||
58.0 |
55.261 |
56.587 |
2.748E-03 |
5.780E-03 |
3.020E-03 |
-5.897E+00 |
-5.153E+00 |
55.236 |
56.534 |
||||||
71.0 |
55.236 |
56.534 |
5.399E-03 |
1.050E-02 |
2.906E-03 |
-5.221E+00 |
-4.557E+00 |
55.186 |
56.436 |
||||||
82.0 |
55.186 |
56.436 |
1.636E-02 |
2.613E-02 |
2.816E-03 |
-4.113E+00 |
-3.645E+00 |
55.045 |
56.209 |
||||||
94.0 |
55.045 |
56.209 |
4.282E-02 |
8.228E-02 |
2.724E-03 |
-3.151E+00 |
-2.498E+00 |
54.696 |
55.533 |
*: Data excluded from the analysis, poor fit to graph
Table 2: Vapour Pressure (VP) Results
|
1/T vs Ln(VP) |
|
Extrapolated VP (Pa) |
||
Test |
Slope |
Intercept |
Correlation |
20 °C |
25 °C |
1 |
-8.877E+03 |
2.090E+01 |
2.090E+01 |
8.381E-05 |
1.393E-04 |
2 |
-8.912E+03 |
2.159E+01 |
-9.865E-01 |
1.486E-04 |
2.474E-04 |
|
Mean of Extrapolated Vapour Pressure |
1.162E-04 |
1.933E-04 |
Description of key information
Under the conditions of the study, the vapour pressure of the test material was determined to be 1.162×10^-4 Pa at 20 °C and 1.933×10^-4 Pa at 25 °C.
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 20 °C
Additional information
The vapour pressure of the test material was investigated in a study which was performed under GLP conditions and in accordance with the standardised guideline OECD 104. The study was assigned a reliability score of 1 in accordance with the criteria for assessing data quality set forth by Klimisch et al. (1997).
The experimental procedure followed the Knudsen cell effusion method. A small quantity of the test substance (nominally 7-9 mg) was placed in each of two weighed aluminium crucibles and a lid, with an orifice of a nominal 1 mm diameter (accurately measured), cold-welded on. The crucibles were weighed to an accuracy of 1 µg and placed in the apparatus, which was then evacuated to ultra-high vacuum. At set time intervals, the apparatus was brought to atmospheric pressure, the crucibles reweighed and the loss in mass of test substance from each calculated. The vapour pressure ¿(Pa) was calculated using the Hertz-Knudsen relationship. Tests were conducted between 58 and 94°C to ensure that test substance remained in the liquid phase throughout the test period. The vapour pressures at 20°C and 25°C were then extrapolated from the vapour pressure-temperature plots.
Under the conditions of the study, the vapour pressure of the test material was determined to be 1.162×10^-4 Pa at 20 °C and 1.933×10^-4 Pa at 25 °C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
