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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
14 November 2016 to 18 January 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
method to determine freezing temperature
Key result
Melting / freezing pt.:
< -20 °C
Remarks on result:
other: freezing temperature

RESULTS

- Cooling data for Determinations 1 and 2 are shown Table 1 and Table 2 (attached).

- Graphs of temperature (K) versus time (s) for Determinations 1 and 2 are shown in Figure 1 and Figure 2 (attached).

Conclusions:
The freezing point of the test item was determined to be less than -20 °C (<253 K).
Executive summary:

GUIDELINE

The determination was carried out by the crystallizing point method, using a procedure designed to be compatible with Method A.1 Melting/Freezing Temperature of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 102 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

 

METHODS          

An aliquot (approximately 15 mL) of test item was placed into a test tube containing a thermometer. A wire loop with which the sample could be agitated was placed inside the tube to ensure sample homogeneity during cooling. The test tube was surrounded by a glass jacket and then placed into a large beaker containing a dry ice/acetone mixture. The temperature and observations of the test item were recorded approximately every 30 seconds. The dry ice/acetone bath was maintained until the sample temperature had reached below -20 °C. The determination was carried out in duplicate.

 

RESULTS

The freezing point of the test item was determined to be less than -20 °C (<253 K).

Description of key information

The freezing point of the research material was determined to be less than -20 °C (<253 K) (OECD 102 and EU Method A.1).

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
-20 °C

Additional information

GUIDELINE

The determination was carried out by the crystallizing point method, using a procedure designed to be compatible with Method A.1 Melting/Freezing Temperature of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 102 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

 

METHODS          

An aliquot (approximately 15 mL) of test item was placed into a test tube containing a thermometer. A wire loop with which the sample could be agitated was placed inside the tube to ensure sample homogeneity during cooling. The test tube was surrounded by a glass jacket and then placed into a large beaker containing a dry ice/acetone mixture. The temperature and observations of the test item were recorded approximately every 30 seconds. The dry ice/acetone bath was maintained until the sample temperature had reached below -20 °C. The determination was carried out in duplicate.

 

RESULTS

The freezing point of the research material was determined to be less than -20 °C (<253 K).