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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Melting point / freezing point

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Administrative data

Link to relevant study record(s)

melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Principles of method if other than guideline:
No information available on test method.
Melting / freezing pt.:
277 °C
Melting point: 277°C (decomposition)

Description of key information

L-histidine decomposes at 277-285°C.

Key value for chemical safety assessment

Additional information

According to reliable handbook references, L-histine decomposes at 277-285°C.