Registration Dossier
Registration Dossier
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EC number: 200-745-3 | CAS number: 71-00-1
Explosiveness
Administrative data
Link to relevant study record(s)
Description of key information
L-histidine does not contain chemical groups that are associated with explosive properties as described in ECHA's Guidance document R7.
As a consequence L-histidine can reasonably be assumed to not exert explosive properties.
Key value for chemical safety assessment
- Explosiveness:
- non explosive
Additional information
In accordance with column 2 of REACH Annex VII the explosive properties of a substance (required in section 7.11) do not need to be tested if there are no chemical groups associated with explosive properties present in the molecule.
When comparing the chemical structure of L-histidine with the chemical groups presented in table R.7.1-28 of section R.7.1.11.3 of ECHA's guidance on "Information requirements and chemical safety assessment" (R7a p. 128), it can be concluded that none of those fragments is present in the substance, and as a consequence there is no structural alert for explosive properties.
Justification for classification or non-classification
Based on the chemical structure of L-histidine, it can be reasonably assumed that the substance will not exert explosive properties.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
