Registration Dossier

Toxicological information

Skin irritation / corrosion

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Administrative data

Endpoint:
skin irritation / corrosion, other
Type of information:
read-across based on grouping of substances (category approach)
Remarks:
polyfluorocarbons
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
publication
Title:
Toxicology of Chlorofluorocarbon Replacements
Author:
Wolfgang Dekant
Year:
1996
Bibliographic source:
Environmental Health Perspectives, Vol 104, Supplement 1, March 1996

Materials and methods

Test guideline
Qualifier:
no guideline followed
Version / remarks:
no information on the method
GLP compliance:
not specified

Results and discussion

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Conclusions:
The Chlorofluorocarbon replacements, i.e. polyfluorocarbons, have a low potential for skin and eye irritation.
No further details provided.
Based on the read across, tetrafluoromethane has a low potential for skin irritation.