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Diss Factsheets
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EC number: 943-325-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 10 August to 14 Augist 1987
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study on liquid formulation according to the guideline, but non-GLP. The tested concentration allows assessment of a reliable value for the LC50
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- GLP compliance:
- no
- Analytical monitoring:
- yes
- Details on sampling:
- At all concentration at 0 and 96 hours
No information on sample storage conditions before analysis - Vehicle:
- no
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Details on test organisms:
- TEST ORGANISM
- Common name: rainbow trout
- Strain:oncorhynchus mykiss
- Source: FORELLENHOF FREDELSLOH, DR.MED.VET. OTTO MUELLER D-3413 MORINGEN 1, Germany
- Age at study initiation (mean and range, SD): no data
- Length at study initiation: 5.1-6.8 cm (mean 5.9 cm)
- Weight at study initiation: 1.5-3.5 g (mean 2.4 g)
- Feeding during test: yes during maintenance ad libitum, food withheld 1 day (not indicated when, but most likely no feeding during the study and 24 hours before start)
- Food type: GROWING FEED F/B50, SSNIFF SPEZIALDIAETEN GMBH, Soest, Germany
ACCLIMATION
- Acclimation period: 7 days
- Acclimation conditions:same as test
- Type and amount of food: see above
- Health during acclimation: no mortality - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Hardness:
- 2.5 MMOL/L
- Test temperature:
- 12-13
- pH:
- 7.3-8.0
- Dissolved oxygen:
- 9.0-11.4 mg/L (82-104% of saturation)
- Salinity:
- NA
- Nominal and measured concentrations:
- nominal: 0, 500 and 1000 mg/L
measured: 0, 506.8 (t=0)/496.2 (t=96) mg/L, 1008.8(t=0)/992.3(t=96) mg/L
results based on nominal concentrations - Details on test conditions:
- TEST SYSTEM
- Test vessel: glass aquarium (80CM X 35CM X 46CM) with 100 L water
- Aeration: no
- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 1
- No. of vessels per control (replicates): 1
- Biomass loading rate: 0.24 g/L
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: reconstituted water
- acid capacity: 0.8 mmol/L
- Na/K: 10:1
- Ca/Mg ratio: 4:1
OTHER TEST CONDITIONS
- Adjustment of pH: no
- Photoperiod: 16 hours light
- Light intensity: no data
EFFECT PARAMETERS MEASURED: at 0, 24, 48, 72 and 96 hours mortality/symptoms (due to extensive colour of the test solutions fish were directed to the front of the glass using a net)
TEST CONCENTRATIONS
- Justification for using less concentrations than requested by guideline: range finding test at 1000 mg/L did not show mortality
- Test concentrations: 0, 500 and 1000 mg/L - Reference substance (positive control):
- no
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 330 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- mortality (fish)
- Details on results:
- no signs of toxicity were observed
- Validity criteria fulfilled:
- yes
- Conclusions:
- The LD50 of the substance is > 100 mg/L
- Executive summary:
10 rainbow trouts/concentration were exposed to a formulation of the test substance at 0, 500 and 1000 mg/L. No mortaity or toxic effects were observed at any of the concentrations tested. Measured concentrations were within 80 -120% of nominal. It can be concluded that the LC50 of the active ingredient is >100 mg/L.
Reference
Description of key information
Ten rainbow trouts/concentration were exposed to a formulation of the test substance at 0, 500 and 1000 mg/L. No mortality or toxic effects were observed at any of the concentrations tested. Measured concentrations were within 80 -120% of nominal. It can be concluded that the LC50 of the active ingredient is >100 mg/L
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 100 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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