Registration Dossier

Administrative data

Key value for chemical safety assessment

Additional information

Justification for selection of genetic toxicity endpoint
No study has been selected as the conclusion that the substance is not genotoxic/mutagenic is based on the three negative studies, the Ames test, the Mouse Lymphoma and the In-vitro human lymphocyte chromosomal aberration studies

Short description of key information:
No significant genotoxicity could be derived for the registration substance by use of read-across appoach. The read-across supporting substance Bis (2-hydroxyethyl) coco alkylamine, CAS 71786 -60 -2 did not show any genotoxic acitivity in three in-vitro tests (Ames test, Chromosome aberration test, and Mouse lymphoma assay).

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

No significant genotoxicity could be derived for the registration substance by use of read-across appoach. The read-across supporting substance Bis (2-hydroxyethyl) coco alkylamine, CAS 71786 -60 -2 did not show any genotoxic acitivity in three in-vitro tests (Ames test, Chromosome aberration test, and Mouse lymphoma assay).

No classification is warranted.