Reaction mass of 3-(3,3-dimethyl-2,3-dihydro-1H-inden-5-yl)propanal and 3-(1,1-dimethyl-2,3-dihydro-1H-inden-5-yl)propanal and 3-(1,1-dimethyl-2,3-dihydro-1H-inden-4-yl)propanal

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2014-07-08 to 2014-07-10

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

The study was conducted in accordance with relevant test method and in compliance with GLP.

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7200 (Melting Point / Melting Range)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

Date of inspection: 2013-01-22/23, Date of signature: 2013-03-22

Type of method:

thermal analysis

Remarks:

Differential Scanning Calorimetry (DSC)

Melting / freezing pt.:

-85 - -75 °C

Atm. press.:

994.1 - 997.8 hPa

Decomposition:

yes

Decomp. temp.:

150 °C

Remarks on result:

other: A melting range of -85 to -75°C was obtained for the substance, however, since onset temperature did not deviate by more than 0.5 K, the mean melting point of the substance was determined to be -80°C at 1013 hPa.

Results:

The DSC results are shown in Table 1 and the thermograms (Figure 1 and Figure 2) are attached.

Table 1: Results of the DSC measurements

No.	Sample weight / mg	Onset of Effect / °C	Range of effect / °C	Air pressure / hPa	Remark
PN7044	9.15	---	---	994.1	Cooling	Figure 1
		-80.13	-85 – -75 (endo)		Heating
PN7061	8.21	---	----	997.8	Cooling	Figure 2
		-80.34	-85 – -75 (endo)		Heating

During the cooling to -100°C no thermal effect could be detected. During the subsequent heating phase a distinct endothermic effect was observed in the temperature range of -85 – -75°C, which can be associated with the melting of the test item. As the onset temperatures in both tests do not deviate by more than 0.5 K from their mean value of -80.24°C, this temperature can be used as melting point. The test item has a melting point of -80°C.

The test item showed further possible exothermic and endothermic effects up to the test end temperature of 500°C, which were not evaluated, since the objective of the study was only the determination of the melting point.

Conclusions:

A mean melting point of -80°C at 1013 hPa was determined for the substance using a relevant test method. The result is considered to be reliable.

Description of key information

Freezing point: -80°C (OECD 102)

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:

-80 °C

Additional information

The melting point of the substance has been determined using relevant test methods and in compliance with GLP. A melting range of -85 to -75°C was obtained for the substance, however, since onset temperature did not deviate by more than 0.5 K, the mean melting point of the substance was determined to be -80°C at 1013 hPa.