Registration Dossier

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

Anthracene gave no evidence of a sensitisation potential in an early hypersensitisation assay with guinea pigs. The result is considered to be valid, as structure-related high-molecular PAHs (3-methylcholanthrene, BaP and 9,10-dimethyl-1,2-benzanthracene), which are known contact sensitisers, gave positive results, whereas no positive reaction was observed with phenanthrene, too.

However, care should be taken in the presence of sun light, since anthracene is phototoxic (see photo-induced skin irritation). The relevance of this property for a possible sensitisation is unclear.

Respiratory sensitisation

Endpoint conclusion
Additional information:
Migrated from Short description of key information:
Based on experimental evidence and occupational experience, no classification as to sensitisation required.

Justification for classification or non-classification