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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Description of key information

Log BCF have been calculated for various representative components of these streams. The calculated values range from 1.2-2.1.

Key value for chemical safety assessment

Additional information

A measured BCF is not available for any streams in this category. As the log Kow of some category members is >3 the bioaccumulation endpoint cannot be waived. However, ECHA's Guidance on Information Requirements and Chemical Safety Assessment R7c Endpoint Specific Guidance (2008) indicates that before commissioning a new vertebrate test alternative sources of data on the bioaccumulation potential of a chemical should used.

Nonpolar substances have been shown to have a linear relationship between log Kow and BCF in the log Kow range 1 -6. Several QSAR have been developed that calculate the BCF of non-polar, hydrophobic compounds on the basis of their log Kow (e. g. Veith et al, 1979 and USEPA, 2008). The streams in this category fall within the applicability domain of these models. The calculated log BCF of representative components of these streams range from 1.2 -2.1.