nitrate amine salt of N-[3-dimethylaminopropyl]- C14-C20 amides, saturated, reaction products with ethylene oxide

Vapour pressure

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 01 December 2016 to 09 December 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Version / remarks:

2009

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Version / remarks:

2006

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7950 (Vapor Pressure)

Version / remarks:

1996

Deviations:

no

GLP compliance:

yes

Type of method:

effusion method: isothermal thermogravimetry

Key result

Temp.:

25 °C

Vapour pressure:

< 0 Pa

Key result

Temp.:

20 °C

Vapour pressure:

< 0 Pa

Conclusions:

The vapour pressure at 25°C was determined to be < 2.1E-08 Pa.
The vapour pressure at 20°C was determined to be < 1.3E-08 Pa.

Executive summary:

The vapour pressure of the substance was determined using the isothermal thermogravimetric effusion method in a GLP study according to EC A.4, OECD 104 and OPPTS 830.7950. The vapour pressure at 25°C was determined to be <2.1E-08 Pa. The vapour pressure at 20°C was determined to be <1.3E-08 Pa.

Reference 2

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 2015-07-24 to 2016-06-24

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

yes

Remarks:

a pan was used instead of a plate

GLP compliance:

not specified

Other quality assurance:

other: ISO 14001

Type of method:

effusion method: isothermal thermogravimetry

Test no.:

#1

Temp.:

50 °C

Vapour pressure:

0.163 Pa

Test no.:

#2

Temp.:

60 °C

Vapour pressure:

0.186 Pa

Test no.:

#3

Temp.:

70 °C

Vapour pressure:

0.21 Pa

Test no.:

#4

Temp.:

80 °C

Vapour pressure:

0.21 Pa

The evaporation rate of the test substance was determined at 5 temperatures between 60 and 175°C. The equation in the plot above was used to calculate the vapor pressure. See results in Table 8.2. The calculated vapor pressure based on evaporation rates was plotted against temperature in order to derive the vapor pressure equation. The calculated vapor pressures were done in mm Hg because all calibration tables were done in this unit. After, the calculated vapor pressures for the test substance were converted to Pascal as per OECD Guideline.

Table 8.2. Experimental evaporation rates of test substance with calculated vapor pressure.

Temp. (°C)	Evaporation Rate (µg/min)	log Evaporation Rate (µg/min)	Temp. (1/K)	Log Vapor Pressure (mmHg)	Calculated Vapor Pressure (mm Hg)	Calculated Vapor Pressure (Pascal)
60	0.0684	-1.164943898	0.003002	-2.855596556	0.001394	0.1859
80	0.0875	-1.057991947	0.002832	-2.745346474	0.001797	0.2396
50	0.0601	-1.221125528	0.003095	-2.913510686	0.001220	0.1627
70	0.0770	-1.113509275	0.002914	-2.802575817	0.001576	0.2101

 

Conclusions:

The vapour pressure of Cyastat SN was determined to be equal to 0.16 Pa at 50°C.

Executive summary:

Density of Cyastat SN has been determined according to OECD test guideline 104. Using TGA method, the vapour pressure of the test substance was determined to be 0.16 Pa at 50 °C.

Description of key information

The vapour pressure at 20°C was determined to be < 1.3E-08 Pa.

The vapour pressure at 25°C was determined to be < 2.1E-08 Pa.

The vapour pressure at 50°C was determinated to be equal to 0.16 Pa.

Key value for chemical safety assessment

Vapour pressure:

0 Pa

at the temperature of:

25 °C

Additional information

Two experimental studies were selected as key study with different temperature.

It was performed according to OECD 104 guideline.

The key value is proposed as < 2.1E-08 Pa at 25°C.