Registration Dossier
Registration Dossier
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EC number: 208-293-9 | CAS number: 520-45-6
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is readily biodegradable
Reference
Description of key information
Hydrolysis is not relevant due to ready biodegradability (RA-A CAS 4418 -26 -2).
Key value for chemical safety assessment
Additional information
No experimental studies investigating the abiotic hydrolysis of the substance are available. However, according to Annex VIII, column 2, 9.2.2.1., Regulation (EC) N° 1907/2006, testing is not required when a substance is readily biodegradable.
A ready biodegradability test (OECD 301 F) is available for a structural analogue of the substance (DHA-Na, CAS 4418-26-2), according to which the substance is readily biodegradable. This is supported by a screening study available in the literature in which the biodegradability of the substance was tested in a range of methods - the coupled units test, the Zahn-Wallens test, the Japanese MITI test, the modified OECD screening test and the closed bottle test. High levels of biodegradability were reported for each test.
Based on read across approach, hydrolysis is therefore not expected to be a relevant pathway.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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