Registration Dossier

Administrative data

Endpoint:
sediment toxicity: short-term
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2011
Report Date:
2012

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: SOP E211 based on OSP AR / P ARC OM Protocols on Methods for the Testing of Chemicals Used in the Offshore Industry 2006 Part A: A sediment bioassay using an amphipod Corophium sp.
Deviations:
no
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Purity: not reported as such

Sampling and analysis

Analytical monitoring:
no

Test organisms

Test organisms (species):
Corophium volutator

Study design

Study type:
laboratory study
Test type:
static
Water media type:
saltwater
Type of sediment:
natural sediment
Exposure duration
Duration:
10 d
Exposure phase:
total exposure duration

Results and discussion

Effect concentrationsopen allclose all
Duration:
10 d
Dose descriptor:
LC50
Effect conc.:
> 12 497 mg/kg sediment dw
Nominal / measured:
nominal
Duration:
10 d
Dose descriptor:
NOEC
Effect conc.:
6 251 mg/kg sediment dw
Nominal / measured:
nominal

Any other information on results incl. tables

The water quality measurements of the test solutions were within acceptable limits during the study.

None of the twenty control Corophium died during the study and this represents an acceptable level of health of the test organisms maintained under test conditions.

Applicant's summary and conclusion

Conclusions:
10-day LC50 of the test substance to Corophium volutator was determined to be > 12497 mg/kg dry sediment.
Executive summary:

The 10-day LC50 of the test substance to Corophium volutator was determined to be > 12497 mg/kg dry sediment by the non-linear interpolation method in ToxCalc™ Version 5.0.

The highest no-observed effect concentration (NOEC) after 10-days was determined to be 6251 mg/kg dry sediment using Fisher's Exact test in ToxCalc™ Version 5.0.

The water quality measurements of the test solutions were within acceptable limits during the study.

None of the twenty control Corophium died during the study and this represents an acceptable level of health of the test organisms maintained under test conditions.