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EC number: 205-788-1 | CAS number: 151-21-3
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
NOEC (42d) >= 1.36 mg/L (measured) for juvenile growth of Pimephales promelas.
Key value for chemical safety assessment
Additional information
Two studies are available investigating the long-term toxicity of sodium dodecyl sulfate (SDS) to freshwater fish.
The key study tested the effects of the test substance in a juvenile fish growth test using Pimephales promelas as test organism (Belanger et al. 1995). Juvenils were exposed over a test period of 42 days to the test substance in a flow-through system using river water. Mortality as well as growth (weight) were recorded. No adverse effects were observed after 42 days of exposure to up to the higest tested concentration of 1.36 mg/L. Thus the 42d-NOEC value is determined to be >= 1.36 mg/L based on measured concentrations.
A second study by Rawlings (2004) investigating the chronic effects on Pimephales promelas was not taken into consideration since already in the lowest tested concentration mortality was observed and hence no reliable NOEC could be derived. An EC10 was extrapolated to be 3.6 mg/L which was below the lowest tested concentration and therefore not considered to be reliable.
Several additional data including tests on marine fish species are mentioned in the OECD SIDS Initial Assessment Report from 2007, however these tests were only subchronic and could not be used for the characterisation of chronic effects on fish (OECD SIDS, 2007).
For the alkyl sulfate categroy several homologues and mixtures with different alkyl chain length were tested in subchronic and chronic tests. The lowest chronic endpoint was observed in an early life stage test conducted by Procter and Gamble in 1987 using a C14 -15 alkyl sulfate (CAS 91648 -54 -3). The reported NOEC for mortality was 0.11 mg/L after 34 days of exposure.
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