Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.176 mg/L
Assessment factor:
5
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
0.055 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.018 mg/L
Assessment factor:
50
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
1.35 mg/L
Assessment factor:
100
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
6.97 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.697 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
1.29 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

For details of PNEC derivation see CSR chapter 7.6 or the justification document for using an assessment factor of 5/50 for deriving the PNEC freshwater/marine water attached in IUCLID chapter 13.

Conclusion on classification

Biodegradation: not readily biodegradable: 95% in 28 d (OECD 301B)

 

Bioaccumulation: The substance has a low potential for bioaccumulation (log Pow < 3).

Aquatic short-term toxicity

96h, LC50 for Pimephales promelas: 29 mg/L (OECD 203); for Cyprinodon variegatus: 4.1 mg/L (ASTM E-35 1980)

48h, EC50 for Ceriodaphnia dubia: 5.55 mg/L (OECD 202); for Artemia salina: 3.15 mg/L (acute toxicity test)

72h, EC50 (Desmodesmus subspicatus): > 120 mg/L (DIN 38412, part 9)

 

Aquatic long-term toxicity

42d, NOEC for Pimephales promelas: >= 1.36 mg/L (42d flow-through test)

7d, NOEC for Ceriodaphnia dubia: 0.88 mg/L (EPA-600/489/001)

72h, NOEC for Desmodesmus subspicatus: 30 mg/L (DIN 38412, part 9)

 

Classification justification according to CLP:

Based on the available data, C12AS Na (CAS 151-21-3) is considered to be rapidly degradable and has low potential for bioaccumulation. The acute aquatic toxicity L(E)C50 are above 1 mg/L for fish, invertebrates and algae. Valid chronic toxicity data are available to fish, invertebrates and algae – the lowest NOEC is 0.88 mg/L (thus in the rage of > 0.1 to < 1 mg/L) for aquatic invertebrates. C12AS Na (CAS 151-21-3) needs to be classified and labeled as environmental hazard Chronic Cat. 3 according to the Regulation (EC) No.1272/2008 (CLP) and the Regulation (EU) No. 286/2011 (2nd ATP).

 

Classification justification according to DSD:

Based on the available data, C12AS Na (CAS 151-21-3) is considered to be rapidly degradable and has a low potential for bioaccumulation. The acute aquatic toxicity L(E)C50 values are above 1 mg/L for fish, invertebrates and algae. C12AS Na (CAS 151-21-3) does not need to be classified and labeled as environmental hazard according to Directive 67/548/EEC.