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Registration Dossier
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EC number: 946-381-5 | CAS number: -
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The substance is readily biodegradable, as observed in a readily biodegradability test according to OECD TG 301B.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
The biodegradation potential of the substance in water was determined in a screening study according to OECD TG 301B (CO2 -Evolution Test) and in compliance with GLP criteria (Charles River, 2017). In this study, 55 mg/L test item (correpsonding to 12 mg TOC/L) was inoculated with activated sludge from predominantly domestic sewage for 28 days under aerobic conditions in the dark. During the incubation period degradation was followed by determining the carbon dioxide produced. In addition, biodegradation of the reference substance sodium acetate (positive control) and inhibitory effects (toxicity control) were determined. Biodegradation of the reference substance was 85% after 14 days. Biodegradation degree of the toxicity control was 71% after 14 days. After the 28-day incubation period, 80% of the test substance was biodegraded. The pass level of 60% degradation was reached within 19 days after the start of the test. Further calculation with mean values of biodegradation indicate the 10-day window was met. Based on these findings, the test substance is classified as readily biodegradable.
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