Registration Dossier
Registration Dossier
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EC number: 279-256-2 | CAS number: 79771-28-1
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
The rate constant (kobs) of Everzol SB26 at 25°C are 3.5× 10-4, 2.77× 10-4 and 1.42× 10-3 hour-1 respectively at pH=4, pH=7 and pH=9. And the half-life time of Everzol SB26 at 25°C are 82.5 days, 104 days and 20.3 days respectively at pH=4, pH=7 and pH=9 (OECD TG111).
Key value for chemical safety assessment
Additional information
In Main study,the mean recoveries of the buffer solutions at pH=4 and t=0 fell within the criterion range of 80 -120% . It demonstrated that the analytical method was adequate to support the hydrolysis study on the test substance. At pH=7, the mean recoveries of the buffer solutions at t=0 fell within the criterion range of 80-110%. At pH=9, the mean recovery of the buffer solutions at t=0 fell within the criterion range of 4.7 -110%. For testing of pseudo-first order kinetics the mean logarithms of the relative concentrations between 10% and 90% were plotted against time. At all temperatures linear relationships were obtained. The half-life times of the test substance were determined according to the model for pseudo-first order reactions. All logarithms of the relative concentrations were correlated with time using linear regression analysis. The rate constant (kobs) and half-life time of the test substance at each temperature was obtained and the Arrhenius equation was used to determine the rate constant and half-life time at 25°C.Therefore, the rate constant (kobs) of Everzol SB26 at 25°C are
3.5× 10-4, 2.77× 10-4 and 1.42× 10-3 hour-1 respectivelyat pH=4, pH=7 and pH=9. And the half-life time of Everzol SB26 at 25°C are 82.5 days, 104 days and 20.3 days respectively at pH=4, pH=7 and pH=9.
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