Registration Dossier

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REACH

Chromate(2-), [2,4-dihydro-4-[(2-hydroxy-4-nitrophenyl)azo]-5-methyl-3H-pyrazol-3-onato(2-)][3-[[4,5-dihydro-3-methyl-1-(4-methylphenyl)-5-oxo-1H-pyrazol-4-yl]azo]-4-hydroxy-5-nitrobenzenesulfonato(3-)]-, disodium

EC number: 278-113-1 | CAS number: 75199-08-5

Life Cycle description
Uses advised against

Toxicological information

Endpoint summary

Administrative data

Description of key information

Skin: No erythema or edema were observed on rabbit skin after 24/48/72 h. The substance is not irritating to skin (score = 0.0). The substance is not classifiable as irritating to skin.

Eye: The substance was tested in an OECD 405 guideline study with three rabbits. The conjunctivae score of 2.3 (24/48/72 h) indicates that the substance causes eye irritation. All symptoms were fully reversible within 21 d. The substance is classifiable as Eye Irritation Category 2.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion

Endpoint conclusion:: no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion

Endpoint conclusion:: adverse effect observed (irritating)

Respiratory irritation

Endpoint conclusion

Endpoint conclusion:: no study available

Additional information

Justification for classification or non-classification

Skin: no irritation occured during the OECD 404 test. The irritation score (erythema/edema) is 0/4. Therefore the substance is not classifiable as irritating to skin.

Eye: eye irritation occured during the OECD 405 test. The irritation score for conjunctivae was 2.3. All symptoms were fully reversible within 21 d. Therefore, the substance is classifiable as irritating to eye (Category 2).

Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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