Registration Dossier

Administrative data

First-aid measures

If inhaled: If breathed in, move person into fresh air. Artificial respiration and/or oxygen may be necessary. Take victim immediately to hospital.
In case of skin contact: Take off contaminated clothing and shoes immediately. Wash off immediately with plenty of water. If symptoms persist, call a physician. Wash contaminated clothing before re-use.
In case of eye contact: Rinse immediately with plenty of water, also under the eyelids, for at least 5 minutes. If eye irritation persists, consult a specialist.
If swallowed: Rinse mouth with water. Call a physician immediately.

Most important symptoms and effects, both acute and delayed
Ingestion may provoke the following symptoms: calming, tremors, relaxation of the muscles

Indication of any immediate medical attention and special treatment needed: Treat symptomatically.

Fire-fighting measures

Suitable extinguishing media: water mist, dry powder, foam, carbon dioxide (CO2), sand, aqueous film forming foam (AFFF).
Unsuitable extinguishing media : water spray jet

Hazardous combustion products: Nitrogen oxides (NOx), Fluorine compounds, Carbon oxides

Special protective equipment for firefighters: In the event of fire, wear self-contained breathing apparatus. Firefighters must wear fire resistant personal protective equipment.

Avoid dust formation.

Accidental release measures

Personal precautions: Evacuate personnel to safe areas. Avoid dust formation. Use personal protective equipment. disposable one-piece overall. Suitable mask with particle filter P3 (European Norm 143)
Environmental precautions: Should not be released into the environment.
Methods for cleaning up: Shovel into suitable container for disposal. Pick up and arrange disposal without creating dust. Keep in properly labelled containers. Keep in suitable, closed containers for disposal. Treat recovered material as described in the section "Disposal Considerations".

Handling and storage

Advice on safe handling: Ensure all equipment is electrically grounded before beginning transfer operations.
Advice on protection against fire and explosion: Avoid dust formation.
Hygiene measures: Handle in accordance with good industrial hygiene and safety practice.
Dust explosion class: St2

Recommended storage temperature: 15 - 25 °C

Transport information

Land transport (ADR/RID)

UN number:
UN 2811
Shippingopen allclose all
Class:
6.1
Classification code:
T2
Packaging group:
III
Labels:
6.1
Remarks:
This substance can be shipped under 'de minimi's quantities' provisions if the net quantity per inner package <= 1mL for liquids or <= 1g for solids and the net quantity per outer package does not exceed 100mL for liquids or 100g for solids and provided packaging provisions of ADR/RID/ADN/IMDG §3.5.1.4 are met.

Inland waterway transport (ADN(R))

UN number:
UN 2811
Shippingopen allclose all
Class:
6.1
Classification code:
T2
Packaging group:
III
Labels:
6.1
Remarks
This substance can be shipped under 'de minimi's quantities' provisions if the net quantity per inner package <= 1mL for liquids or <= 1g for solids and the net quantity per outer package does not exceed 100mL for liquids or 100g for solids and provided packaging provisions of ADR/RID/ADN/IMDG §3.5.1.4 are met.

Marine transport (IMDG)

UN number:
UN 2811
Proper shipping name and description:
TOXIC SOLID, ORGANIC, N.O.S.
((Z)-3-[2-[4-[(2,4-difluorophenyl)(hydroxyimino)methyl]-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one.)
Chemical name:
(Z)-3-[2-[4-[(2,4-difluorophenyl)(hydroxyimino)methyl]-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Class:
6.1
Packaging group:
III
EmS code:
F-A, S-A
Labels:
6.1
Remarks
This substance can be shipped under 'de minimi's quantities' provisions if the net quantity per inner package <= 1mL for liquids or <= 1g for solids and the net quantity per outer package does not exceed 100mL for liquids or 100g for solids and provided packaging provisions of ADR/RID/ADN/IMDG §3.5.1.4 are met.

Air transport ICAO/IATA

UN number:
UN 2811
Proper shipping name and description:
Toxic solid, organic, n.o.s.
((Z)-3-[2-[4-[(2,4-difluorophenyl)(hydroxyimino)methyl]-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one.)
Chemical name:
(Z)-3-[2-[4-[(2,4-difluorophenyl)(hydroxyimino)methyl]-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Class:
6.1
Packaging group:
III
Labels:
6.1
Remarks
This substance can be shipped under 'de minimi's quantities' provisions if the net quantity per inner package <= 1mL for liquids or <= 1g for solids and the net quantity per outer package does not exceed 100mL for liquids or 100g for solids and provided packaging provisions of IATA DGR §2.6.10 are met.
SpecialProvisionsopen allclose all

Exposure controls / personal protection

Personal protective equipment
Eye protection: Tightly fitting safety goggles
Hand protection: Nitrile rubber. Take note of the information given by the producer concerning permeability and break through times, and of special workplace conditions (mechanical strain, dura-tion of contact).
Skin and body protection: closed work clothing, disposable one-piece overall
Respiratory protection: Engineering controls should always be the primary method of controlling exposures. If respiratory protective equipment is needed for certain activi-ties, the type as well as the corresponding protection factor will depend upon the risk assessment and air concentrations, hazards, physical and warning properties of substances pre-sent. Use only respiratory protection that conforms to international/ national standards. Suitable mask with particle filter P3
Protective measures: The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Stability and reactivity

Reactivity: None reasonably foreseeable.
Chemical stability: Stable under recommended storage conditions.
Possibility of hazardous reactions: Hazardous polymerisation does not occur.
Conditions to avoid: No data available
Incompatible materials (materials to avoid): Oxidizing agents
Hazardous decomposition products: Carbon oxides, Fluorocarbons, Nitrogen oxides (NOx)

Disposal considerations

Waste treatment methods: In accordance with local and national regulations.