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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
11-07-2017 – 15-07-2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
Experimental test result performed using standard test guidelines
Qualifier:
according to
Guideline:
other: spectrophotometric analytical method
Principles of method if other than guideline:
The water solubility determination of test item 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7) was done as per the OECD guideline 105 byspectrophotometric analytical method as per OECD 101.
GLP compliance:
no
Type of method:
other: spectrophotometric analytical method
Specific details on test material used for the study:
- Name of test material: 5-amino-2-chlorobenzenesulfonic acid
- Molecular formula: C6H6ClNO3S
- Molecular weight: 207.636 g/mol
- Smiles notation: S(c1c(ccc(c1)N)Cl)(O)(=O)=O
- InChl: 1S/C6H6ClNO3S/c7-5-2-1-4(8)3-6(5)12(9,10)11/h1-3H,8H2,(H,9,10,11)
- Substance type: Organic
- Physical state: Solid
Key result
Water solubility:
3 656.1 mg/L
Conc. based on:
test mat.
Temp.:
25 °C
Remarks on result:
other: No other detail available

Obseravtionn Table:

Sample stirring

Concentration obtained on

Dilution factor

Solubility value obtained

 

the basis of standard curve

 

(mg/L)

24 hour

-

-

-

48 hour

36.494

100

3649.4

72 hour

36.628

100

3662.8

Conclusions:
The water solubility determination of test item 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7) was done as per
the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The solubility of (5 -amino-2 -
chlorobenzenesulphonic acid of 88 -43 -7 )in water was found to be 3656.1 mg/L at 25°C. Thus 5 -amino-2 -chlorobenzenesulphonic acid is considered to be soluble in water.
Executive summary:

The water solubility determination of test item 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7) was done as per

the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The solubility of (5 -amino-2 -

chlorobenzenesulphonic acid of 88 -43 -7 )in water was found to be 3656.1 mg/L at 25°C. Thus 5 -amino-2 -chlorobenzenesulphonic acid is considered to be soluble in water.

Description of key information

The water solubility determination of test item 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7) was done as per

the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The solubility of (5 -amino-2 -

chlorobenzenesulphonic acid of 88 -43 -7 )in water was found to be 3656.1 mg/L at 25°C. Thus 5 -amino-2 -chlorobenzenesulphonic acid is considered to be soluble in water.

Key value for chemical safety assessment

Water solubility:
3 656.1 mg/L
at the temperature of:
25 °C

Additional information

The water solubility determination of test item 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7) was done as per

the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The solubility of (5 -amino-2 -

chlorobenzenesulphonic acid of 88 -43 -7 )in water was found to be 3656.1 mg/L at 25°C. Thus 5 -amino-2 -chlorobenzenesulphonic acid is considered to be soluble in water.

Water solubility of the 5 -amino-2 -chlorobenzenesulfonic acid is determined from above source is 11310 mg/L at 0 Deg C.

Based on the above solubility values, the 5 -amino-2 -chlorobenzenesulfonic acid was slightly soluble in water.

It is concluted that 5-amino-2-chlorobenzenesulfonic acid is very soluble in water.