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EC number: 201-830-8 | CAS number: 88-43-7
Endpoint summary
Administrative data
Description of key information
Appearance:
On the basis of physical observation and using the sense of smell, 5-amino-2-chlorobenzenesulphonic acid was observed to be a solid white powder.
Melting point:
The melting point determination of Test item 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7 ) was done as per the test guideline OECD 102. The method followed was according to Capillary/metal block. The Mean Melting Temperature Range was determine to be 290-295.1°C at 963.8 hPa.
Boiling Point:
The boiling point determination of Test item 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7 ) was done as per the test guideline OECD 103. The method followed was according to Siwoloboff. The test item melts above 290 deg C , hence the boiling point could not be determined.
Density:
The density of Test item 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7 ) was determined following OECD guideline 109 and according to the method recommended in the International Pharmacopoeia, fourth Edition, 2014. The pour
density and tapped density of the test item was determine to be 0.4349 g/cm³ and 0.6669 g/cm³ at 25.3°C and 961.95 hPa.
Particle size distribution:
The particle size distribution of test item 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7 ) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determine to bein the range of 150 micron to 106 micron.
Vapour pressure:
The estimated vapour pressure of 5 -amino-2-chlorobenzenesulfonic acid at 25 deg C was 0.0000058 Pa
Partition coefficient:
The Partition coefficient (POw) on soil and on sewage sludge of the 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7) was determine to be 0.056±0.129 at 25 °C.
Water solubility:
The water solubility determination of test item 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7) was done as per the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The solubility of (5 -amino-2 - chlorobenzenesulphonic acid of 88 -43 -7 )in water was found to be 3656.1 mg/L at 25°C. Thus 5 -amino-2 -chlorobenzenesulphonic acid is considered to be soluble in water.
Surface tension:
Surface tension of 5-amino-2-chlorobenzenesulfonic acid from above authorative database is predicted to be 69.7 mN/m.
Flash point:
The flash point determination of Test item 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7 )was done. The method was closed cup method using Pensky-Martens Flash Point Apparatus. The mean flash point of the test item was determine to be 161.3°C at 964.8 hPa.
Auto flammability:
5-amino-2-chlorobenzenesulfonic acid did not catch fire on being exposed to air at room temperature of 27 °C pressure of 966 hPa. This indicates that 5 -amino-2 -chlorobenzenesulfonic acid is not auto-flammable.
Flammability:
5-amino-2-chlorobenzenesulfonic acid does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 5 -amino-2 -chlorobenzenesulfonic acid is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 5 -amino-2 -chlorobenzenesulfonic acid was considered non-flammable.
Explosiveness:
the study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties
Oxidizing properties:
the study does not need to be conducted because the organic substance contains oxygen or halogen atoms which are chemically bonded only to carbon or hydrogen and hence, the classification procedure does not need to be applied
pH:
The pH determination of test item 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7 ) was done as per the test guideline OECD 122. The mean pH of the test solutionwas determined with the help of digital pH meter. The mean pH was determine to be 2.16 at 26.8 °C.
Additional information
Appearance:
On the basis of physical observation and using the sense of smell, 5-amino-2-chlorobenzenesulphonic acid was observed to be a solid white powder.
Based on the various observations test chemical 5-amino-2-chlorobenzenesulfonic acid physically appear in solid state which are in crystalline white needles form. From the other reliable source it is concluded that 5 -amino-2 -chlorobenzenesulfonic acid is physically appear to be a solid powder form which is white to gray in colour.
Melting point:
The melting point determination of Test item 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7 ) was done as per the test guideline OECD 102. The method followed was according to Capillary/metal block. The Mean Melting Temperature Range was determine to be 290-295.1°C at 963.8 hPa.
From the other authorative database melting point of 5 -amino-2 -chlorobenzenesulfonic acid is greater than 310 Deg C.
Decomposition temperature of chemical 5-amino-2 -chlorobenzenesulfonic acid is determined to be 280.0 Deg C
Boiling Point:
The boiling point determination of Test item 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7 ) was done as per the test guideline OECD 103. The method followed was according to Siwoloboff. The test item melts above 290 deg C , hence the boiling point could not be determined.
Density:
The density of Test item 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7 ) was determined following OECD guideline 109 and according to the method recommended in the International Pharmacopoeia, fourth Edition, 2014. The pour density and tapped density of the test item was determine to be 0.4349 g/cm³ and 0.6669 g/cm³ at 25.3°C and 961.95 hPa.
From other reliable sources density of 5-amino-2 -chlorobenzenesulfonic acid is concluded to be 1.3501 g/cm3 at temperature 25 Deg C. With these study other authorative databases concluded density of chemical 5 -amino-2 -chlorobenzenesulfonic acid to be 1.642 g/cm3 at 20 Deg C and pressure 760 torr.
Particle size distribution:
The particle size distribution of test item 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7 ) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determine to bein the range of 150 micron to 106 micron.
Vapour pressure:
The estimated vapour pressure of the 5-amino-2-chlorobenzenesulfonic acid at 25 deg C was 0.0000058
Partition coefficient:
The partition Coefficient n-octanol/water of 5-amino-2-chlorobenzenesulphonic acid(CAS No.88-43-7) at 25 °C was estimated according to the OECD Guideline No. 107, adopted on 27th July 1995,”Shake Flask Method” Shake-flask Method The Solubility of 5-amino-2 -chlorobenzenesulphonic acid(CAS No.88-43-7) was determined in-house and it was found to be 3656.1 mg/l. For the Pow estimation, the different volumes of a stock solution (noctanol pre saturated with water) were shaken with different volume of water pre saturated with n-octanol. After centrifugation, both the aqueous phase and octanol phase were analysed by HPLC. The partition coefficient were calculated, from the measured concentration of 5-amino-2-chlorobenzenesulphonic acid(CAS No.88-43-7) in the organic and aqueous phases. The log Pow value was found to be 0.056±0.129 at 25 °C
By considering this log Pow value it can be concluded that 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7) is hydrophilic in nature and it is also supported by high water solubility of test chemical in water.
Based on the available data from authoritative databases and handbook, the partition coefficient (log Pow) value of the substance 5 -amino-2 -chlorobenzenesulfonic acid was estimated to be -1.44. Based on the estimated value, the chemical 5 -amino-2 -chlorobenzenesulfonic acid can be considered to be hydrophilic in nature.
Water solubility:
The water solubility determination of test item 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7) was done as per the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The solubility of (5 -amino-2 - chlorobenzenesulphonic acid of 88 -43 -7 )in water was found to be 3656.1 mg/L at 25°C. Thus 5 -amino-2 -chlorobenzenesulphonic acid is considered to be soluble in water.
Water solubility of the 5 -amino-2 -chlorobenzenesulfonic acid is determined from above source is 11310 mg/L at 0 Deg C.
Based on the above solubility values, the 5 -amino-2 -chlorobenzenesulfonic acid was slightly soluble in water.
It is concluted that 5-amino-2-chlorobenzenesulfonic acid is very soluble in water.
Surface tension:
Surface tension of 5-amino-2-chlorobenzenesulfonic acid from above authorative database is predicted to be 69.7 mN/m.
Flash point:
The flash point determination of Test item 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7 )was done. The method was closed cup method using Pensky-Martens Flash Point Apparatus. The mean flash point of the test item was determine to be 161.3°C at 964.8 hPa.
Auto flammability:
5-amino-2-chlorobenzenesulfonic acid did not catch fire on being exposed to air at room temperature of 27 °C pressure of 966 hPa. This indicates that 5 -amino-2 -chlorobenzenesulfonic acid is not auto-flammable.
Flammability:
5-amino-2-chlorobenzenesulfonic acid does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 5 -amino-2 -chlorobenzenesulfonic acid is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 5 -amino-2 -chlorobenzenesulfonic acid was considered non-flammable.
Explosiveness:
the study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties
Oxidizing properties:
the study does not need to be conducted because the organic substance contains oxygen or halogen atoms which are chemically bonded only to carbon or hydrogen and hence, the classification procedure does not need to be applied
pH:
The pH determination of test item 5-amino-2-chlorobenzenesulphonic acid (CAS No. 88-43-7 ) was done as per the test guideline OECD 122. The mean pH of the test solutionwas determined with the help of digital pH meter. The mean pH was determine to be 2.16 at 26.8 °C.
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