Registration Dossier

Administrative data

Hazard for aquatic organisms

Hazard for air

Hazard for terrestrial organisms

Hazard for predators

Additional information

Conclusion on classification

The 72-hour EC50 and NOEC in algae are 0.42 and 0.025 mg/L, respectively. The 7-day EC50 and NOEC (growth rate) in the aquatic plant, Lemna gibba, are 0.000808 and 0.000129 mg/L, respectively. Additionally, the substance is considered not rapidly degradable. Therefore, the test substance is classified as Acute Cat 1 (H400: Very toxic to aquatic life) and Chronic Cat 1 (H410: Very toxic to aquatic life with long lasting effects) according to EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.

In accordance with article 10 of the CLP Regulation (EC) No 1272/2008, if an M-factor is not yet given in Part 3 of Annex VI to the CLP Regulation, an M-factor should be determined and a scientific justification provided, when classifying substances for Acute Category 1 or Chronic Category 1. For this substance, adequate acute aquatic data are available in fish, aquatic invertebrates, and algae/aquatic plants. An Acute M-Factor is based on the lowest reported effects in the most sensitive species, the aquatic plant, Lemna gibba. Therefore, the M factor is 1000 based on the 7-day EC50 in the aquatic plant, Lemna gibba, of 0.000808 mg/L.

In accordance with article 10 of the CLP Regulation (EC) No 1272/2008, if an M-factor is not yet given in Part 3 of Annex VI to the CLP Regulation, an M-factor should be determined and a scientific justification provided, when classifying substances for Acute Category 1 or Chronic Category 1. Chronic data were available in fish, invertebrates, and algae/aquatic plants. The lowest reported effects in chronic data were the 7 d NOEC data of 0.000129 mg/L in the aquatic plant, Lemna gibba. The test substance is Not biodegradable. Therefore, the M factor is 100.