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EC number: 209-548-7
CAS number: 585-07-9
No signs of dermal irritation were detected during the 14 post-exposure period.
A GLP-compliant acute dermal toxicity of the test material in the Sprague-Dawley CD strain rat was conducted according to OECD guideline 402 and EU method B3. A total of 10 animals (5 males and 5 females) were given a single, 24-hour, semi-occluded dermal application of the undiluted test material to intact skin at a dose level of 2000 mg/kg body weight. Clinical signs, bodyweight development, and dermal irritation were monitored during the study. All animals were subjected to gross necropsy. At each observation time point and following necropsy, there were no signs of dermal irritation or systemic toxicity. All animals showed expected gains in body weight over the study period. The acute LD50 of the test material In the Sprague-Dawley CD strain rat was found to be greater than 2000 mg/kg bw.
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