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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
30-Nov-2015 to 04-Dec-2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reference:
Composition 0
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
yes (incl. certificate)
Remarks:
Staatliches Gewerbeaufsichtsamt Hildeshelm
Type of method:
flask method
Test material information:
Composition 1
Key result
Water solubility:
3.9 g/L
Temp.:
20 °C
pH:
4.7

Results

Preliminary Test (non GLP)

The solubility was determined to be in the range of 2.06 - 4.12 g/L; no Tyndall-effect was observed at 2.06 g/L. For the application dose for the definitive study, approx. 20 g/L, as ca. the fivefold of the maximum solubility result, was used.

 

Main test

Water solubility results at 20 °C

Pre-incubation time

Replicate No.

Concentration1)

(g/L)

Mean

24 h

1

3.95

3.94

2

3.94

48 h

1

3.92

3.86

2

3.80

72 h

1

3.90

3.91

2

3.91

Mean (24 – 72 h)

 

 

3.90

Deviation (%)2)

 

 

2.1

 

1) Mean value of double injections, dilution factor of 200 and exact weights taken into account

2) Calculated according to the formula:

Deviation (%) =100 x (max value – min value)

                                      min value

Mean pH value = 4.7

Conclusions:
A water solubility value of 3.90 g/L (at 20 °C, pH 4.7) was determined for the test substance according to E.U. Method A.6.

Description of key information

Water solubility: 3.90 g/L at 20 °C, pH = 4.7 (EU Method A.6., flask method)

Key value for chemical safety assessment

Water solubility:
3.9 g/L
at the temperature of:
20 °C

Additional information