2-Propenoic acid, 2-methyl-, 7-oxabicyclo[4.1.0]hept-3-ylmethyl ester

Biodegradation in water: screening tests

Administrative data

Endpoint:

biodegradation in water: ready biodegradability

Type of information:

experimental study

Adequacy of study:

key study

Study period:

12 August 2014 - 10 September 2014

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Guideline study and GLP

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2014

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

2-Propenoic acid, 2-methyl-, 7-oxabicyclo[4.1.0]hept-3-ylmethyl ester

IUPAC Name:

2-Propenoic acid, 2-methyl-, 7-oxabicyclo[4.1.0]hept-3-ylmethyl ester

Study design

Oxygen conditions:

aerobic

Inoculum or test system:

activated sludge, domestic, non-adapted

Duration of test (contact time):

28 d

Initial test substance concentration

Initial conc.:

23 mg/L

Based on:

test mat.

Parameter followed for biodegradation estimation

Parameter followed for biodegradation estimation:

O2 consumption

Results and discussion

% Degradation

Parameter:

% degradation (O2 consumption)

Value:

99

Sampling time:

28 d

Remarks on result:

other: Parallel 1

Details on results:

Biodegradation [%] of the Test Item S-100, 3,4-Epoxycyclohexylmethyl methacrylate in Comparison to the Functional Control and Toxicity Control
Biodegradation [%]
Study Day [d]
Replicate 7 14 21 28
Test Item 23 mg/L
1 25 60 90 99
2 25 49 79 90
Functional Control
45 mg/L 86 97 100 100
Toxicity Control
23 mg/L Test Item +
45 mg/L Reference Item 62 82 88 92

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Interpretation of results:

readily biodegradable

Conclusions:

Both test item replicates reached the 10 % level (beginning of biodegradation) on day 5. At test end the biodegradation of the 1st replicate reached 99 % and of the 2nd replicate 90 %. The mean biodegradation after 28 days was 95%. The 60 % pass level was reached by the mean of replicates on day 16. The 10-d-window was missed marginally by the mean of replicates, but the first replicate complied to the 10-d-window (day 5 to day 14). As a consequence, the test item is considered to be readily biodegradable.

Executive summary:

Both test item replicates reached the 10 % level (beginning of biodegradation) on day 5. At test end the biodegradation of the 1^streplicate reached 99 % and of the 2^ndreplicate 90 %. The mean biodegradation after 28 days was 95%. The 60 % pass level was reached by the mean of replicates on day 16. The 10-d-window was missed marginally by the mean of replicates, but the first replicate complied to the 10-d-window (day 5 to day 14). As a consequence, the test item is considered to be readily biodegradable.