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EC number: 943-389-0 | CAS number: -
Test item concentration of individual replicates and mean; percentage of hydrolysis. In(Ct/C0) used for the calculations of the rate constants.
pH 4 and 50 °C
pH 7 and 50 °C
pH 9 and 50 °C
The hydrolysis of the substance was investigated in a preliminary test (Tier 1) according to TG OECD 111 by incubating solutions of about 50 mg test item/l at three environmentally relevant pH values (pH 4, 7 and 9) and 50 °C over five days.
The results obtained under the test conditions are summarized in the table below, which gives the determined hydrolysis rate constants (kobs) and calculated half-lifes including 95 % confidence intervals (CI):
Hydrolysis of the test item was only observed at pH 4, with a half-life of 2.30 days. At pH 7 and 9, no significant decrease of the test item concentrations was found over the duration of the test.
According to the guideline, a second hydrolysis study (Tier 2) has to be conducted at the pH values where the test item hydrolyses and at different temperatures. In accordance with the sponsor and since the test item is readily biodegradable, no Tier 2 study was conducted.
Hydrolysis of test item was only observed at pH 4, with an half-life of 2.30 days. At pH values of 7 and 9 no hydrolysis was observed.
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