Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2016
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
yes (incl. certificate)
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
3.1 - 3.4
Temp.:
35 °C
pH:
7

Applicant's summary and conclusion

Conclusions:
In the conditions of the test, the chromatograms of GR-50-3010 show two peaks at average retention times of 4.923 minutes (6.5% relative peak area), corresponding to a partition coefficient (log value) of 3.1 and 5.598 minutes (93.5% relative peak area), corresponding to a partition coefficient (log value) of 3.4.


Therefore:


Partition coefficients n-octanol/water of GR-50-3010:

log Pow = 3.1 and 3.4